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Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

Hydrocarbon stapling is a chemical approach to restoring and fortifying the natural α-helical structure of peptides that otherwise unfold when taken out of context from the host protein. By iterating the peptide sequence, staple type, and sites of insertion, discrete compositions can be generated to...

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Main Authors: Bird, Greg H., Gavathiotis, Evripidis, LaBelle, James L., Katz, Samuel G., Walensky, Loren D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4131438/
https://ncbi.nlm.nih.gov/pubmed/24358963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb4003305
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