Photoreactive Stapled BH3 Peptides to Dissect the BCL-2 Family Interactome

Defining protein interactions forms the basis for discovery of biological pathways, disease mechanisms, and opportunities for therapeutic intervention. To harness the robust binding affinity and selectivity of structured peptides for interactome discovery, we engineered photoreactive stapled BH3 pep...

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Main Authors: Braun, Craig R., Mintseris, Julian, Gavathiotis, Evripidis, Bird, Gregory H., Gygi, Steven P., Walensky, Loren D.
Format: Artigo
Jezik:Inglês
Izdano: 2010
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048092/
https://ncbi.nlm.nih.gov/pubmed/21168768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.09.015
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