Flow Cytometry-Based Detection and Analysis of BCL-2 Family Proteins and Mitochondrial Outer Membrane Permeabilization (MOMP)

por Ludwig, Lindsey M., Maxcy, Katrina L., LaBelle, James L.
Publicado en Methods Mol Biol (2019)

Killing Two Cells with One Stone: Pharmacologic BCL-2 Family Targeting for Cancer Cell Death and Immune Modulation

por Ludwig, Lindsey M., Nassin, Michele L., Hadji, Abbas, LaBelle, James L.
Publicado en Front Pediatr (2016)

Synthesis and Purification of Homogeneous Lipid-Based Peptide Nanocarriers by Overcoming Phospholipid Ester Hydrolysis

por Schnorenberg, Mathew R., Yoo, Sang Pil, Tirrell, Matthew V., LaBelle, James L.
Publicado en ACS Omega (2018)

Loss of BIM in T cells results in BCL-2 family BH3-member compensation but incomplete cell death sensitivity normalization

por Ludwig, Lindsey M., Roach, Lauren E., Katz, Samuel G., LaBelle, James L.
Publicado en Apoptosis (2020)

RNA Polymerase tags to monitor multidimensional protein-protein interactions reveal pharmacological engagement of Bcl-2 proteins

por Pu, Jinyue, Dewey, Jeffrey A., Hadji, Abbas, LaBelle, James L., Dickinson, Bryan C.
Publicado en J Am Chem Soc (2017)

Distinct BimBH3 (BimSAHB) Stapled Peptides for Structural and Cellular Studies

por Bird, Greg H., Gavathiotis, Evripidis, LaBelle, James L., Katz, Samuel G., Walensky, Loren D.
Publicado 2014

Activating the Intrinsic Pathway of Apoptosis Using BIM BH3 Peptides Delivered by Peptide Amphiphiles with Endosomal Release

por Schnorenberg, Mathew R., Bellairs, Joseph A., Samaeekia, Ravand, Acar, Handan, Tirrell, Matthew V., LaBelle, James L.
Publicado en Materials (Basel) (2019)

Cathepsin-Mediated Cleavage of Peptides from Peptide Amphiphiles Leads to Enhanced Intracellular Peptide Accumulation

por Acar, Handan, Samaeekia, Ravand, Schnorenberg, Mathew R., Sasmal, Dibyendu K, Huang, Jun, Tirrell, Matthew V., LaBelle, James L.
Publicado en Bioconjug Chem (2017)

Self-Assembling Peptide-Based Building Blocks in Medical Applications

por Acar, Handan, Srivastava, Samanvaya, Chung, Eun Ji, Schnorenberg, Mathew R., Barrett, John C., LaBelle, James L., Tirrell, Matthew
Publicado en Adv Drug Deliv Rev (2016)

Multimodal Interaction with BCL-2 Family Proteins Underlies the Pro-Apoptotic Activity of PUMA BH3

por Edwards, Amanda L., Gavathiotis, Evripidis, LaBelle, James L., Braun, Craig R., Opoku-Nsiah, Kwadwo A., Bird, Gregory H., Walensky, Loren D.
Publicado 2013

Preferential targeting of MCL-1 by a hydrocarbon-stapled BIM BH3 peptide

por Hadji, Abbas, Schmitt, Greta K., Schnorenberg, Mathew R., Roach, Lauren, Hickey, Connie M., Leak, Logan B., Tirrell, Matthew V., LaBelle, James L.
Publicado en Oncotarget (2019)

Mantle cell lymphoma in cyclin D1 transgenic mice with Bim-deficient B cells

por Katz, Samuel G., LaBelle, James L., Meng, Hailong, Valeriano, Regina P., Fisher, Jill K., Sun, Heather, Rodig, Scott J., Kleinstein, Steven H., Walensky, Loren D.
Publicado 2014

A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers

por LaBelle, James L., Katz, Samuel G., Bird, Gregory H., Gavathiotis, Evripidis, Stewart, Michelle L., Lawrence, Chelsea, Fisher, Jill K., Godes, Marina, Pitter, Kenneth, Kung, Andrew L., Walensky, Loren D.
Publicado 2012

Outcomes following second allogeneic stem cell transplant for disease relapse after T cell depleted transplant correlate with remission status and remission duration after the firs...

por Fan, Yun, Artz, Andrew S., van Besien, Koen, Stock, Wendy, Larson, Richard A., Odenike, Olatoyosi, Godley, Lucy A., Kline, Justin, Cunningham, John M., LaBelle, James L., Bishop, Michael R., Liu, Hongtao
Publicado en Exp Hematol Oncol (2019)

Repression of BIM mediates survival signaling by MYC and AKT in high-risk T-cell acute lymphoblastic leukemia

por Reynolds, Christine, Roderick, Justine E., LaBelle, James L., Bird, Gregory, Mathieu, Ronald, Bodaar, Kimberly, Colon, Diana, Pyati, Ujwal, Stevenson, Kristen E., Qi, Jun, Harris, Marian, Silverman, Lewis B., Sallan, Stephen E., Bradner, James E., Neuberg, Donna S., Look, A. Thomas, Walensky, Loren D., Kelliher, Michelle A., Gutierrez, Alejandro
Publicado 2014

Polymersomes decorated with SARS-CoV-2 spike protein receptor binding domain elicit robust humoral and cellular immunity

por Volpatti, Lisa R., Wallace, Rachel P., Cao, Shijie, Raczy, Michal M., Wang, Ruyi, Gray, Laura T., Alpar, Aaron T., Briquez, Priscilla S., Mitrousis, Nikolaos, Marchell, Tiffany M., Sasso, Maria Stella, Nguyen, Mindy, Mansurov, Aslan, Budina, Erica, Solanki, Ani, Watkins, Elyse A., Schnorenberg, Mathew R., Tremain, Andrew C., Reda, Joseph W., Nicolaescu, Vlad, Furlong, Kevin, Dvorkin, Steve, Yu, Shann S., Manicassamy, Balaji, LaBelle, James L., Tirrell, Matthew V., Randall, Glenn, Kwissa, Marcin, Swartz, Melody A., Hubbell, Jeffrey A.
Publicado en bioRxiv (2021)

Polymersomes Decorated with the SARS-CoV-2 Spike Protein Receptor-Binding Domain Elicit Robust Humoral and Cellular Immunity

por Volpatti, Lisa R., Wallace, Rachel P., Cao, Shijie, Raczy, Michal M., Wang, Ruyi, Gray, Laura T., Alpar, Aaron T., Briquez, Priscilla S., Mitrousis, Nikolaos, Marchell, Tiffany M., Sasso, Maria Stella, Nguyen, Mindy, Mansurov, Aslan, Budina, Erica, Solanki, Ani, Watkins, Elyse A., Schnorenberg, Mathew R., Tremain, Andrew C., Reda, Joseph W., Nicolaescu, Vlad, Furlong, Kevin, Dvorkin, Steve, Yu, Shann S., Manicassamy, Balaji, LaBelle, James L., Tirrell, Matthew V., Randall, Glenn, Kwissa, Marcin, Swartz, Melody A., Hubbell, Jeffrey A.
Publicado en ACS Cent Sci (2021)