Slowing muscle atrophy: putting the brakes on protein breakdown

Por Lecker, Stewart H, Goldberg, Alfred L
Publicado em 2002

Proteolysis in illness-associated skeletal muscle atrophy: from pathways to networks

Por Wing, Simon S., Lecker, Stewart H., Jagoe, R. Thomas
Publicado no Crit Rev Clin Lab Sci (2011)

Calpain activity and muscle wasting in sepsis

Por Smith, Ira J., Lecker, Stewart H., Hasselgren, Per-Olof
Publicado em 2008

Construction and Analysis of Mouse Strains Lacking the Ubiquitin Ligase UBR1 (E3α) of the N-End Rule Pathway

Por Kwon, Yong Tae, Xia, Zanxian, Davydov, Ilia V., Lecker, Stewart H., Varshavsky, Alexander
Publicado em 2001

Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

Por Gomes, Marcelo D., Lecker, Stewart H., Jagoe, R. Thomas, Navon, Ami, Goldberg, Alfred L.
Publicado em 2001

Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect

Por Cao, Peirang, Hanai, Jun-ichi, Tanksale, Preeti, Imamura, Shintaro, Sukhatme, Vikas P., Lecker, Stewart H.
Publicado em 2009

Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats

Por Lecker, Stewart H., Solomon, Vered, Price, S. Russ, Kwon, Yong Tae, Mitch, William E., Goldberg, Alfred L.
Publicado em 1999

PGC-1α protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

Por Sandri, Marco, Lin, Jiandie, Handschin, Christoph, Yang, Wenli, Arany, Zoltan P., Lecker, Stewart H., Goldberg, Alfred L., Spiegelman, Bruce M.
Publicado em 2006

Foxo Transcription Factors Induce the Atrophy-Related Ubiquitin Ligase Atrogin-1 and Cause Skeletal Muscle Atrophy

Por Sandri, Marco, Sandri, Claudia, Gilbert, Alex, Skurk, Carsten, Calabria, Elisa, Picard, Anne, Walsh, Kenneth, Schiaffino, Stefano, Lecker, Stewart H., Goldberg, Alfred L.
Publicado em 2004

The muscle-specific ubiquitin ligase atrogin-1/MAFbx mediates statin-induced muscle toxicity

Por Hanai, Jun-ichi, Cao, Peirang, Tanksale, Preeti, Imamura, Shintaro, Koshimizu, Eriko, Zhao, Jinghui, Kishi, Shuji, Yamashita, Michiaki, Phillips, Paul S., Sukhatme, Vikas P., Lecker, Stewart H.
Publicado em 2007

MECHANISMS UNDERLYING SKELETAL MUSCLE WEAKNESS IN HUMAN HEART FAILURE: ALTERATIONS IN SINGLE FIBER MYOSIN PROTEIN CONTENT AND FUNCTION

Por Miller, Mark S., VanBuren, Peter, LeWinter, Martin M., Lecker, Stewart H., Selby, Donald E., Palmer, Bradley M., Maughan, David W., Ades, Philip A., Toth, Michael J.
Publicado em 2009

Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

Por Mearini, Giulia, Gedicke, Christina, Schlossarek, Saskia, Witt, Christian C., Krämer, Elisabeth, Cao, Peirang, Gomes, Marcelo D., Lecker, Stewart H., Labeit, Siegfried, Willis, Monte S., Eschenhagen, Thomas, Carrier, Lucie
Publicado em 2010

Jade-1 inhibits Wnt signaling by ubiquitinating β-catenin and mediates Wnt pathway inhibition by pVHL

Por Chitalia, Vipul C., Foy, Rebecca L., Bachschmid, Markus M., Zeng, Liling, Panchenko, Maria V., Zhou, Mina I., Bharti, Ajit, Seldin, David C., Lecker, Stewart H., Dominguez, Isabel, Cohen, Herbert T.
Publicado em 2008

Analysis of Skeletal Muscle Gene Expression Patterns and the Impact of Functional Capacity in Patients With Systolic Heart Failure

Por FORMAN, DANIEL E., DANIELS, KARLA M., CAHALIN, LAWRENCE P., ZAVIN, ALEXANDRA, ALLSUP, KELLY, CAO, PEIRANG, SANTHANAM, MAHALAKSHMI, JOSEPH, JACOB, ARENA, ROSS, LAZZARI, ANTONIO, SCHULZE, P. CHRISTIAN, LECKER, STEWART H.
Publicado no J Card Fail (2014)

Myosin Light Chain Phosphorylation is Critical for Adaptation to Cardiac Stress

Por Warren, Sonisha A., Briggs, Laura E., Zeng, Huadong, Chuang, Joyce, Chang, Eileen I., Terada, Ryota, Li, Moyi, Swanson, Maurice S., Lecker, Stewart H., Willis, Monte S., Spinale, Francis G., Maupin-Furlow, Julie, McMullen, Julie R., Moss, Richard L., Kasahara, Hideko
Publicado em 2012

A branched chain amino acid metabolite drives vascular transport of fat and causes insulin resistance

Por Jang, Cholsoon, Oh, Sungwhan F, Wada, Shogo, Rowe, Glenn C, Liu, Laura, Chan, Mun Chun, Rhee, James, Hoshino, Atsushi, Kim, Boa, Ibrahim, Ayon, Baca, Luisa G, Kim, Esl, Ghosh, Chandra C, Parikh, Samir M, Jiang, Aihua, Chu, Qingwei, Forman, Daniel E., Lecker, Stewart H., Krishnaiah, Saikumari, Rabinowitz, Joshua D, Weljie, Aalim M, Baur, Joseph A, Kasper, Dennis L, Arany, Zoltan
Publicado no Nat Med (2016)