Atrogin-1, a muscle-specific F-box protein highly expressed during muscle atrophy

Muscle wasting is a debilitating consequence of fasting, inactivity, cancer, and other systemic diseases that results primarily from accelerated protein degradation by the ubiquitin-proteasome pathway. To identify key factors in this process, we have used cDNA microarrays to compare normal and atrop...

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Bibliographic Details
Main Authors: Gomes, Marcelo D., Lecker, Stewart H., Jagoe, R. Thomas, Navon, Ami, Goldberg, Alfred L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC64700/
https://ncbi.nlm.nih.gov/pubmed/11717410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251541198
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