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Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms
AIMS: Familial hypertrophic cardiomyopathy (FHC) is frequently caused by cardiac myosin-binding protein C (cMyBP-C) gene mutations, which should result in C-terminal truncated mutants. However, truncated mutants were not detected in myocardial tissue of FHC patients and were rapidly degraded by the...
Gorde:
| Egile Nagusiak: | , , , , , , , , , , , |
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| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
Oxford University Press
2010
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023316/ https://ncbi.nlm.nih.gov/pubmed/19850579 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp348 |
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