Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

AIMS: Familial hypertrophic cardiomyopathy (FHC) is frequently caused by cardiac myosin-binding protein C (cMyBP-C) gene mutations, which should result in C-terminal truncated mutants. However, truncated mutants were not detected in myocardial tissue of FHC patients and were rapidly degraded by the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Mearini, Giulia, Gedicke, Christina, Schlossarek, Saskia, Witt, Christian C., Krämer, Elisabeth, Cao, Peirang, Gomes, Marcelo D., Lecker, Stewart H., Labeit, Siegfried, Willis, Monte S., Eschenhagen, Thomas, Carrier, Lucie
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2010
Gaiak:
Original Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023316/
https://ncbi.nlm.nih.gov/pubmed/19850579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp348
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak