Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1

MuRF1 is an E3 ubiquitin ligase central to muscle catabolism. It belongs to the TRIM protein family characterized by a tripartite fold of RING, B-box and coiled-coil (CC) motifs, followed by variable C-terminal domains. The CC motif is hypothesized to be responsible for domain organization in the fo...

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Detalhes bibliográficos
Main Authors: Franke, Barbara, Gasch, Alexander, Rodriguez, Dayté, Chami, Mohamed, Khan, Muzamil M., Rudolf, Rüdiger, Bibby, Jaclyn, Hanashima, Akira, Bogomolovas, Julijus, von Castelmur, Eleonore, Rigden, Daniel J., Uson, Isabel, Labeit, Siegfried, Mayans, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3971405/
https://ncbi.nlm.nih.gov/pubmed/24671946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.130172
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