Atrogin-1 and MuRF1 regulate cardiac MyBP-C levels via different mechanisms

AIMS: Familial hypertrophic cardiomyopathy (FHC) is frequently caused by cardiac myosin-binding protein C (cMyBP-C) gene mutations, which should result in C-terminal truncated mutants. However, truncated mutants were not detected in myocardial tissue of FHC patients and were rapidly degraded by the...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Mearini, Giulia, Gedicke, Christina, Schlossarek, Saskia, Witt, Christian C., Krämer, Elisabeth, Cao, Peirang, Gomes, Marcelo D., Lecker, Stewart H., Labeit, Siegfried, Willis, Monte S., Eschenhagen, Thomas, Carrier, Lucie
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4023316/
https://ncbi.nlm.nih.gov/pubmed/19850579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp348
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados