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Statin-induced muscle damage and atrogin-1 induction is the result of a geranylgeranylation defect
Statins are widely used to treat hypercholesterolemia but can lead to a number of side effects in muscle, including rhabdomyolysis. Our recent findings implicated the induction of atrogin-1, a gene required for the development of muscle atrophy, in statin-induced muscle damage. Since statins inhibit...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
The Federation of American Societies for Experimental Biology
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2735363/ https://ncbi.nlm.nih.gov/pubmed/19406843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-128843 |
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