Viral oncoprotein-induced mislocalization of select PDZ proteins disrupts tight junctions and causes polarity defects in epithelial cells

Por Latorre, Isabel J., Roh, Michael H., Frese, Kristopher K., Weiss, Robert S., Margolis, Ben, Javier, Ronald T.
Publicado em 2005

Selective PDZ protein-dependent stimulation of phosphatidylinositol 3-kinase by the adenovirus E4-ORF1 oncoprotein

Por Frese, Kristopher K, Lee, Siu Sylvia, Thomas, Darby L, Latorre, Isabel J, Weiss, Robert S, Glaunsinger, Britt A, Javier, Ronald T
Publicado em 2003

Oncogenic function for the Dlg1 mammalian homolog of the Drosophila discs-large tumor suppressor

Por Frese, Kristopher K, Latorre, Isabel J, Chung, Sang-Hyuk, Caruana, Georgina, Bernstein, Alan, Jones, Stephen N, Donehower, Lawrence A, Justice, Monica J, Garner, Craig C, Javier, Ronald T
Publicado em 2006

SELECTIVE INDUCTION OF HOMEOSTATIC TH17 CELLS IN THE MURINE INTESTINE BY CHOLERA TOXIN INTERACTING WITH THE MICROBIOTA

Por ZHAO, QING, HARBOUR, STACEY N., KOLDE, RAIVO, LATORRE, ISABEL J., TUN, HEIN M., SCHOEB, TRENTON R., TURNER, HENRIETTA, MOON, JAMES J., KHAFIPOUR, EHSAN, XAVIER, RAMNIK J., WEAVER, CASEY T., ELSON, CHARLES O.
Publicado no J Immunol (2017)

Discovery of a Small-Molecule Probe for V-ATPase Function

Por Aldrich, Leslie N., Kuo, Szu-Yu, Castoreno, Adam B., Goel, Gautam, Kuballa, Petric, Rees, Matthew G., Seashore-Ludlow, Brinton A., Cheah, Jaime H., Latorre, Isabel J., Schreiber, Stuart L., Shamji, Alykhan F., Xavier, Ramnik J.
Publicado no J Am Chem Soc (2015)

Development of Chemical Probes for Investigation of Salt-Inducible Kinase Function In Vivo

Por Sundberg, Thomas B., Liang, Yanke, Wu, Huixian, Choi, Hwan Geun, Kim, Nam Doo, Sim, Taebo, Johannessen, Liv, Petrone, Adam, Khor, Bernard, Graham, Daniel B., Latorre, Isabel J., Phillips, Andrew J., Schreiber, Stuart L., Perez, Jose, Shamji, Alykhan F., Gray, Nathanael S., Xavier, Ramnik J.
Publicado no ACS Chem Biol (2016)

Small-molecule studies identify CDK8 as a regulator of IL-10 in myeloid cells

Por Johannessen, Liv, Sundberg, Thomas B, O’Connell, Daniel J, Kolde, Raivo, Berstler, James, Billings, Katelyn J, Khor, Bernard, Seashore-Ludlow, Brinton, Fassl, Anne, Russell, Caitlin N, Latorre, Isabel J, Jiang, Baishan, Graham, Daniel B, Perez, Jose R, Sicinski, Piotr, Phillips, Andrew J, Schreiber, Stuart L, Gray, Nathanael S, Shamji, Alykhan F, Xavier, Ramnik J
Publicado no Nat Chem Biol (2017)