Cystathionine β-synthase Deficiency: Of Mice and Men

Por Kruger, Warren D.
Publicado no Mol Genet Metab (2017)

Suppression of Tumor Formation by a COX-2 Inhibitor and a PPARγ Agonist in an in vivo Mouse Model of Spontaneous Breast Cancer

Por Mustafa, Aladdin, Kruger, Warren D.
Publicado em 2008

Cystathionine Beta-Synthase Deficiency Causes Fat Loss in Mice

Por Gupta, Sapna, Kruger, Warren D.
Publicado em 2011

The effect of dietary modulation of sulfur amino acids on cystathionine β synthase–deficient mice

Por Kruger, Warren D., Gupta, Sapna
Publicado no Ann N Y Acad Sci (2015)

Functional Rescue of Mutant Human Cystathionine β-Synthase by Manipulation of Hsp26 and Hsp70 Levels in Saccharomyces cerevisiae

Por Singh, Laishram R., Kruger, Warren D.
Publicado em 2009

Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice

Por Gupta, Sapna, Wang, Liqun, Kruger, Warren D.
Publicado no J Inherit Metab Dis (2015)

The c.797 G>A (p.R266K) Cystathionine β-Synthase Mutation Causes Homocystinuria by Affecting Protein Stability

Por Gupta, Sapna, Wang, Liqun, Kruger, Warren D
Publicado no Hum Mutat (2017)

Increasing the therapeutic index of 5-fluorouracil and 6-thioguanine by targeting loss of MTAP in tumor cells

Por Tang, Baiqing, Testa, Joseph R., Kruger, Warren D.
Publicado em 2012

The Herp Protein Pathway is Not Involved in the Pro-Amyloidogenic Effect of Hyperhomocysteinemia

Por Zhuo, Jia-Min, Kruger, Warren D., Praticò, Domenico
Publicado em 2010

Cystathionine β-synthase-deficient mice thrive on a low-methionine diet

Por Gupta, Sapna, Melnyk, Stepan B., Kruger, Warren D.
Publicado em 2014

Chemical chaperone rescue of mutant human cystathionine β-synthase

Por Singh, Laishram R., Chen, Xulin, Kožich, Viktor, Kruger, Warren D.
Publicado em 2007

The TSC1/2 Complex Controls Drosophila Pigmentation through TORC1-Dependent Regulation of Catecholamine Biosynthesis

Por Zitserman, Diana, Gupta, Sapna, Kruger, Warren D., Karbowniczek, Magdalena, Roegiers, Fabrice
Publicado em 2012

Expression of MTAP Inhibits Tumor-Related Phenotypes in HT1080 Cells via a Mechanism Unrelated to Its Enzymatic Function

Por Tang, Baiqing, Kadariya, Yuwaraj, Chen, Yibai, Slifker, Michael, Kruger, Warren D.
Publicado no G3 (Bethesda) (2014)

Hydroxychloroquine Destabilizes Phospho-S6 in Human Renal Carcinoma Cells

Por Lee, Hyung-Ok, Mustafa, Aladdin, Hudes, Gary R., Kruger, Warren D.
Publicado no PLoS One (2015)

Combination of serum histidine and plasma tryptophan as a potential biomarker to detect clear cell renal cell carcinoma

Por Lee, Hyung-Ok, Uzzo, Robert G., Kister, Debra, Kruger, Warren D.
Publicado no J Transl Med (2017)

Testing computational prediction of missense mutation phenotypes: Functional characterization of 204 mutations of human cystathionine beta synthase

Por Wei, Qiong, Wang, Liqun, Wang, Qiang, Kruger, Warren D., Dunbrack, Roland L.
Publicado em 2010

Quantitation of Cellular Metabolic Fluxes of Methionine

Por Shlomi, Tomer, Fan, Jing, Tang, Baiqing, Kruger, Warren D., Rabinowitz, Joshua D.
Publicado em 2014

Regulation of human methylthioadenosine phosphorylase gene by the CBF (CCAAT binding factor)/NF-Y (nuclear factor-Y)

Por Kadariya, Yuwaraj, Nakatani, Kaname, Nishioka, Junji, Fujikawa, Takahiko, Kruger, Warren D., Nobori, Tsutomu
Publicado em 2005

Valproic acid increases expression of methylenetetrahydrofolate reductase (MTHFR) and induces lower teratogenicity in MTHFR deficiency

Por Roy, Marc, Leclerc, Daniel, Wu, Qing, Gupta, Sapna, Kruger, Warren D., Rozen, Rima
Publicado em 2008

Active Cystathionine β-Synthase Can Be Expressed in Heme-free Systems in the Presence of Metal-substituted Porphyrins or a Chemical Chaperone

Por Majtan, Tomas, Singh, Laishram R., Wang, Liqun, Kruger, Warren D., Kraus, Jan P.
Publicado em 2008