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Suppression of Tumor Formation by a COX-2 Inhibitor and a PPARγ Agonist in an in vivo Mouse Model of Spontaneous Breast Cancer

PURPOSE: Activation of cyclooxygenase-2 (COX-2) and inhibition of peroxisome proliferators-activated receptor γ (PPARγ) have been observed in human and animal models of breast cancer. Both inhibition of COX-2 and activation of PPARγ can inhibit proliferation of breast cancer cells in vitro. Here we...

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Detalhes bibliográficos
Main Authors: Mustafa, Aladdin, Kruger, Warren D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2587271/
https://ncbi.nlm.nih.gov/pubmed/18676768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-08-0958
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