A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses

BACKGROUND: Persistent fibroblast activation initiated by transforming growth factor β (TGF-β) is a fundamental event in the pathogenesis of systemic sclerosis (SSc), and its pharmacological inhibition represents a potential therapeutic strategy. The nuclear receptor peroxisome proliferator-activate...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Wei, Jun, Zhu, Hongyan, Komura, Kazuhiro, Lord, Gabriel, Tomcik, Michal, Wang, Wenxia, Doniparthi, Sruthi, Tamaki, Zenshiro, Hinchcliff, Monique, Distler, Joerg H. W., Varga, John
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4028127/
https://ncbi.nlm.nih.gov/pubmed/23515440
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-202716
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items