Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment

Liver fibrosis interferes with normal liver function and facilitates hepatocellular carcinoma (HCC) development, representing a major threat to human health. Here, we present a comprehensive perspective of microRNA (miRNA) function on targeting the fibrotic microenvironment. Starting from a murine H...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Winkler, Ivana, Bitter, Catrin, Winkler, Sebastian, Weichenhan, Dieter, Thavamani, Abhishek, Hengstler, Jan G., Borkham-Kamphorst, Erawan, Kohlbacher, Oliver, Plass, Christoph, Geffers, Robert, Weiskirchen, Ralf, Nordheim, Alfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2020
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955372/
https://ncbi.nlm.nih.gov/pubmed/31871210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909145117
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