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Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

In most vertebrates, the liver produces bile that is necessary to emulsify absorbed fats and enable the digestion of lipids in the small intestine as well as to excrete bilirubin and other metabolic products. In the liver, the experimental obstruction of the extrahepatic biliary system initiates a c...

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Publicat a:J Vis Exp
Autors principals: Tag, Carmen G., Sauer-Lehnen, Sibille, Weiskirchen, Sabine, Borkham-Kamphorst, Erawan, Tolba, René H., Tacke, Frank, Weiskirchen, Ralf
Format: Artigo
Idioma:Inglês
Publicat: MyJove Corporation 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354634/
https://ncbi.nlm.nih.gov/pubmed/25741630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52438
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