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Pharmacological Intervention in Hepatic Stellate Cell Activation and Hepatic Fibrosis
The activation and transdifferentiation of hepatic stellate cells (HSCs) into contractile, matrix-producing myofibroblasts (MFBs) are central events in hepatic fibrogenesis. These processes are driven by autocrine- and paracrine-acting soluble factors (i.e., cytokines and chemokines). Proof-of-conce...
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| Publicado no: | Front Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764688/ https://ncbi.nlm.nih.gov/pubmed/26941644 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2016.00033 |
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