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Deleterious effect of oltipraz on extrahepatic cholestasis in bile duct-ligated mice
BACKGROUND & AIMS: Oltipraz (4-methyl-5(pyrazinyl-2)-1-2-dithiole-3-thione), a promising cancer preventive agent, has an anti-oxidative activity and ability to enhance glutathione biosynthesis, phase II detoxification enzymes and multidrug resistance-associated protein-mediated efflux transporte...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4054607/ https://ncbi.nlm.nih.gov/pubmed/23978715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jhep.2013.08.015 |
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