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Mouse organic solute transporter α deficiency enhances renal excretion of bile acids and attenuates cholestasis

Organic solute transporter alpha-beta (Ostα-Ostβ) is a heteromeric bile acid and sterol transporter that facilitates the entero- and renal-hepatic circulation of bile acids. Hepatic expression of this basolateral membrane protein is increased in cholestasis, presumably to facilitate removal of toxic...

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Autori principali: Soroka, Carol J., Mennone, Albert, Hagey, Lee R., Ballatori, Nazzareno, Boyer, James L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819820/
https://ncbi.nlm.nih.gov/pubmed/19902485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.23265
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