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All-Trans-Retinoic Acid Improves Cholestasis in α-Naphthylisothiocyanate–Treated Rats and Mdr2(−/−) Mice

Chronic cholestasis results in liver injury and eventually liver failure. Although ursodeoxycholic acid (UDCA) showed limited benefits in primary biliary cirrhosis, there is an urgent need to develop alternative therapy for chronic cholestatic disorders. Previous studies from our laboratory demonstr...

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Bibliografiske detaljer
Main Authors: Cai, Shi-Ying, Mennone, Albert, Soroka, Carol J., Boyer, James L.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Pharmacology and Experimental Therapeutics 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3965885/
https://ncbi.nlm.nih.gov/pubmed/24492652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.113.209353
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