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Cenicriviroc, a cytokine receptor antagonist, potentiates all-trans retinoic acid in reducing liver injury in cholestatic rodents

BACKGROUND & AIMS: Cholestatic liver injury is mediated by bile acid induced inflammatory responses. We hypothesized that superior therapeutic effects might be achieved by combining treatments that reduce the bile acid pool size with one that blocks inflammation. METHODS: Bile duct ligated (BDL)...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Yu, Dongke, Cai, Shi-Ying, Mennone, Albert, Vig, Pamela, Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032984/
https://ncbi.nlm.nih.gov/pubmed/29356312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13698
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