Cenicriviroc, a cytokine receptor antagonist, potentiates all-trans retinoic acid in reducing liver injury in cholestatic rodents

BACKGROUND & AIMS: Cholestatic liver injury is mediated by bile acid induced inflammatory responses. We hypothesized that superior therapeutic effects might be achieved by combining treatments that reduce the bile acid pool size with one that blocks inflammation. METHODS: Bile duct ligated (BDL)...

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Bibliographic Details
Published in:Liver Int
Main Authors: Yu, Dongke, Cai, Shi-Ying, Mennone, Albert, Vig, Pamela, Boyer, James L.
Format: Artigo
Language:Inglês
Published: 2018
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6032984/
https://ncbi.nlm.nih.gov/pubmed/29356312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.13698
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