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The antagonistically bifunctional retinoid oxidoreductase complex is required for maintenance of all-trans-retinoic acid homeostasis

All-trans-retinoic acid (RA), a bioactive derivative of vitamin A, exhibits diverse effects on gene transcription and non-genomic regulatory pathways. The steady-state levels of RA are therefore tightly controlled, but the mechanisms responsible for RA homeostasis are not fully understood. We report...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Belyaeva, Olga V., Adams, Mark K., Wu, Lizhi, Kedishvili, Natalia Y.
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2017
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5392580/
https://ncbi.nlm.nih.gov/pubmed/28232491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.776914
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