Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

UAB30 is an RXR selective agonist that has been shown to have potential cancer chemopreventive properties. Due to high efficacy and low toxicity, it is currently being evaluated in human Phase I clinical trials by the National Cancer Institute. While UAB30 shows promise as a low toxicity chemopreven...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Wu, Lizhi, Chaudhary, Sandeep C., Atigadda, Venkatram R., Belyaeva, Olga V., Harville, Steven R., Elmets, Craig A., Muccio, Donald D., Athar, Mohammad, Kedishvili, Natalia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831765/
https://ncbi.nlm.nih.gov/pubmed/27078158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153556
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