Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

UAB30 is an RXR selective agonist that has been shown to have potential cancer chemopreventive properties. Due to high efficacy and low toxicity, it is currently being evaluated in human Phase I clinical trials by the National Cancer Institute. While UAB30 shows promise as a low toxicity chemopreven...

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Publicat a:PLoS One
Autors principals: Wu, Lizhi, Chaudhary, Sandeep C., Atigadda, Venkatram R., Belyaeva, Olga V., Harville, Steven R., Elmets, Craig A., Muccio, Donald D., Athar, Mohammad, Kedishvili, Natalia Y.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831765/
https://ncbi.nlm.nih.gov/pubmed/27078158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153556
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