Retinoid X Receptor Agonists Upregulate Genes Responsible for the Biosynthesis of All-Trans-Retinoic Acid in Human Epidermis

UAB30 is an RXR selective agonist that has been shown to have potential cancer chemopreventive properties. Due to high efficacy and low toxicity, it is currently being evaluated in human Phase I clinical trials by the National Cancer Institute. While UAB30 shows promise as a low toxicity chemopreven...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wu, Lizhi, Chaudhary, Sandeep C., Atigadda, Venkatram R., Belyaeva, Olga V., Harville, Steven R., Elmets, Craig A., Muccio, Donald D., Athar, Mohammad, Kedishvili, Natalia Y.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4831765/
https://ncbi.nlm.nih.gov/pubmed/27078158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0153556
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