The Retinoid X Receptor Agonist, 9-cis UAB30, Inhibits Cutaneous T-cell Lymphoma Proliferation Through the SKP2-p27kip1 Axis

BACKGROUND: Bexarotene (Targretin®) is currently the only FDA approved retinoid X receptor (RXR) -selective agonist for the treatment of cutaneous T-cell lymphomas (CTCLs). The main side effects of bexarotene are hypothyroidism and elevation of serum triglycerides (TGs). The novel RXR ligand, 9-cis...

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Publicado no:J Dermatol Sci
Main Authors: Chou, Chu-Fang, Hsieh, Yu-Hua, Grubbs, Clinton J., Atigadda, Venkatram R., Mobley, James A., Dummer, Reinhard, Muccio, Donald D., Eto, Isao, Elmets, Craig A., Garvey, W. Timothy, Chang, Pi-Ling
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6329374/
https://ncbi.nlm.nih.gov/pubmed/29599065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jdermsci.2018.03.006
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