Effects on Gene Expression in Rat Liver after Administration of RXR Agonists: UAB30, 4-Methyl-UAB30, and Targretin (Bexarotene)

Examination of three retinoid X receptor (RXR) agonists [Targretin (TRG), UAB30, and 4-methyl-UAB30 (4-Me-UAB30)] showed that all inhibited mammary cancer in rodents and two (TRG and 4-Me-UAB30) strikingly increased serum triglyceride levels. Agents were administered in diets to female Sprague-Dawle...

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Detalhes bibliográficos
Main Authors: Vedell, Peter T., Lu, Yan, Grubbs, Clinton J., Yin, Yuxin, Jiang, Hui, Bland, Kirby I., Muccio, Donald D., Cvetkovic, Dusica, You, Ming, Lubet, Ronald
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3583492/
https://ncbi.nlm.nih.gov/pubmed/23292798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.112.082404
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