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The Retinaldehyde Reductase Activity of DHRS3 Is Reciprocally Activated by Retinol Dehydrogenase 10 to Control Retinoid Homeostasis

The retinoic acid-inducible dehydrogenase reductase 3 (DHRS3) is thought to function as a retinaldehyde reductase that controls the levels of all-trans-retinaldehyde, the immediate precursor for bioactive all-trans-retinoic acid. However, the weak catalytic activity of DHRS3 and the lack of changes...

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Detalhes bibliográficos
Main Authors: Adams, Mark K., Belyaeva, Olga V., Wu, Lizhi, Kedishvili, Natalia Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4031538/
https://ncbi.nlm.nih.gov/pubmed/24733397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.552257
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