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Retinol dehydrogenase 11 is essential for the maintenance of retinol homeostasis in liver and testis in mice

Retinol dehydrogenase 11 (RDH11) is a microsomal short-chain dehydrogenase/reductase that recognizes all-trans– and cis–retinoids as substrates and prefers NADPH as a cofactor. Previous work has suggested that RDH11 contributes to the oxidation of 11-cis–retinol to 11-cis–retinaldehyde during the vi...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Belyaeva, Olga V., Wu, Lizhi, Shmarakov, Igor, Nelson, Peter S., Kedishvili, Natalia Y.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5936824/
https://ncbi.nlm.nih.gov/pubmed/29567832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001646
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