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Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

The transcription factor nuclear factor-E2-related factor 2 (Nrf2) is a key regulator for induction of hepatic detoxification and antioxidant mechanisms, as well as for certain hepatobiliary transporters. To examine the role of Nrf2 in bile acid homeostasis and cholestasis, we assessed the determina...

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Detalhes bibliográficos
Main Authors: Weerachayaphorn, Jittima, Mennone, Albert, Soroka, Carol J., Harry, Kathy, Hagey, Lee R., Kensler, Thomas W., Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362073/
https://ncbi.nlm.nih.gov/pubmed/22345550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00263.2011
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