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Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine

The transcription factor nuclear factor-E2-related factor 2 (Nrf2) is a key regulator for induction of hepatic detoxification and antioxidant mechanisms, as well as for certain hepatobiliary transporters. To examine the role of Nrf2 in bile acid homeostasis and cholestasis, we assessed the determina...

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Hlavní autoři: Weerachayaphorn, Jittima, Mennone, Albert, Soroka, Carol J., Harry, Kathy, Hagey, Lee R., Kensler, Thomas W., Boyer, James L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Physiological Society 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3362073/
https://ncbi.nlm.nih.gov/pubmed/22345550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00263.2011
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