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Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression
Multidrug resistance protein 4 (MRP4; ABCC4) is an ATP binding cassette transporter that facilitates the excretion of bile salt conjugates and other conjugated steroids in hepatocytes and renal proximal tubule epithelium. MRP4/Mrp4 undergoes adaptive upregulation in response to oxidative and cholest...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904108/ https://ncbi.nlm.nih.gov/pubmed/20395535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00522.2010 |
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