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Nuclear receptors RXRα:RARα are repressors for human MRP3 expression
Multidrug resistance associated protein MRP3/Mrp3 (ABCC3) is upregulated in cholestasis, an adaptive response that may protect the liver from accumulation of toxic compounds, such as bile salts and bilirubin conjugates. However, the mechanism of this upregulation is poorly understood. We and others...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605854/ https://ncbi.nlm.nih.gov/pubmed/17272513 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00191.2006 |
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