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Nuclear receptors RXRα:RARα are repressors for human MRP3 expression

Multidrug resistance associated protein MRP3/Mrp3 (ABCC3) is upregulated in cholestasis, an adaptive response that may protect the liver from accumulation of toxic compounds, such as bile salts and bilirubin conjugates. However, the mechanism of this upregulation is poorly understood. We and others...

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Detalhes bibliográficos
Main Authors: Chen, Wensheng, Cai, Shi-Ying, Xu, Shuhua, Denson, Lee A., Soroka, Carol J., Boyer, James L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2605854/
https://ncbi.nlm.nih.gov/pubmed/17272513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00191.2006
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