Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis

In most vertebrates, the liver produces bile that is necessary to emulsify absorbed fats and enable the digestion of lipids in the small intestine as well as to excrete bilirubin and other metabolic products. In the liver, the experimental obstruction of the extrahepatic biliary system initiates a c...

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Bibliographic Details
Published in:J Vis Exp
Main Authors: Tag, Carmen G., Sauer-Lehnen, Sibille, Weiskirchen, Sabine, Borkham-Kamphorst, Erawan, Tolba, René H., Tacke, Frank, Weiskirchen, Ralf
Format: Artigo
Language:Inglês
Published: MyJove Corporation 2015
Subjects:
Medicine
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354634/
https://ncbi.nlm.nih.gov/pubmed/25741630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52438
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