Identification of Pparγ-modulated miRNA hubs that target the fibrotic tumor microenvironment

Liver fibrosis interferes with normal liver function and facilitates hepatocellular carcinoma (HCC) development, representing a major threat to human health. Here, we present a comprehensive perspective of microRNA (miRNA) function on targeting the fibrotic microenvironment. Starting from a murine H...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Winkler, Ivana, Bitter, Catrin, Winkler, Sebastian, Weichenhan, Dieter, Thavamani, Abhishek, Hengstler, Jan G., Borkham-Kamphorst, Erawan, Kohlbacher, Oliver, Plass, Christoph, Geffers, Robert, Weiskirchen, Ralf, Nordheim, Alfred
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2020
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6955372/
https://ncbi.nlm.nih.gov/pubmed/31871210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1909145117
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