Regulation of human methylthioadenosine phosphorylase gene by the CBF (CCAAT binding factor)/NF-Y (nuclear factor-Y)

hMTAP (human 5′-deoxy-5′-methylthioadenosine phosphorylase) is a key enzyme in the methionine salvage pathway and is frequently inactivated in human tumour cells. To understand the mechanism of the transcriptional regulation of the MTAP gene, we have cloned the 1.29 kb fragment of the hMTAP promoter...

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Détails bibliographiques
Auteurs principaux: Kadariya, Yuwaraj, Nakatani, Kaname, Nishioka, Junji, Fujikawa, Takahiko, Kruger, Warren D., Nobori, Tsutomu
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2005
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134945/
https://ncbi.nlm.nih.gov/pubmed/15535799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041472
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