Regulation of human methylthioadenosine phosphorylase gene by the CBF (CCAAT binding factor)/NF-Y (nuclear factor-Y)

hMTAP (human 5′-deoxy-5′-methylthioadenosine phosphorylase) is a key enzyme in the methionine salvage pathway and is frequently inactivated in human tumour cells. To understand the mechanism of the transcriptional regulation of the MTAP gene, we have cloned the 1.29 kb fragment of the hMTAP promoter...

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Detaylı Bibliyografya
Asıl Yazarlar: Kadariya, Yuwaraj, Nakatani, Kaname, Nishioka, Junji, Fujikawa, Takahiko, Kruger, Warren D., Nobori, Tsutomu
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Portland Press Ltd. 2005
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134945/
https://ncbi.nlm.nih.gov/pubmed/15535799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041472
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