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Regulation of human methylthioadenosine phosphorylase gene by the CBF (CCAAT binding factor)/NF-Y (nuclear factor-Y)

hMTAP (human 5′-deoxy-5′-methylthioadenosine phosphorylase) is a key enzyme in the methionine salvage pathway and is frequently inactivated in human tumour cells. To understand the mechanism of the transcriptional regulation of the MTAP gene, we have cloned the 1.29 kb fragment of the hMTAP promoter...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kadariya, Yuwaraj, Nakatani, Kaname, Nishioka, Junji, Fujikawa, Takahiko, Kruger, Warren D., Nobori, Tsutomu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Portland Press Ltd. 2005
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1134945/
https://ncbi.nlm.nih.gov/pubmed/15535799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20041472
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