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Betaine supplementation is less effective than methionine restriction in correcting phenotypes of CBS deficient mice
Cystathionine beta synthase (CBS) deficiency is a recessive inborn error of metabolism characterized by elevated serum total homocysteine (tHcy). Betaine supplementation, which can lower tHcy by stimulating homocysteine remethylation to methionine, is often given to CBS deficient patients in combina...
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| Publicado no: | J Inherit Metab Dis |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4784539/ https://ncbi.nlm.nih.gov/pubmed/26231230 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10545-015-9883-z |
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