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Cystathionine Beta-Synthase Deficiency Causes Fat Loss in Mice

Cystathionine beta synthase (CBS) is the rate-limiting enzyme responsible for the de novo synthesis of cysteine. Patients with CBS deficiency have greatly elevated plasma total homocysteine (tHcy), decreased levels of plasma total cysteine (tCys), and often a marfanoid appearance characterized by th...

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Bibliographic Details
Main Authors: Gupta, Sapna, Kruger, Warren D.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214081/
https://ncbi.nlm.nih.gov/pubmed/22096601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0027598
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