Integrated Approaches for Genome-wide Interrogation of the Druggable Non-olfactory G Protein-coupled Receptor Superfamily

Autor Roth, Bryan L., Kroeze, Wesley K.
Vydáno v J Biol Chem (2015)

Deorphanization of Novel Peptides and Their Receptors

Autor Ozawa, Akihiko, Lindberg, Iris, Roth, Bryan, Kroeze, Wesley K.
Vydáno 2010

Tuning up the right signal: chemical and genetic approaches to study GPCR functions

Autor Giguere, Patrick M., Kroeze, Wesley K., Roth, Bryan L.
Vydáno 2013

Antagonist Functional Selectivity: 5-HT(2A) Serotonin Receptor Antagonists Differentially Regulate 5-HT(2A) Receptor Protein Level In Vivo

Autor Yadav, Prem N., Kroeze, Wesley K., Farrell, Martilias S., Roth, Bryan L.
Vydáno 2011

Discovery and Characterization of Novel GPR39 Agonists Allosterically Modulated by Zinc

Autor Sato, Seiji, Huang, Xi-Ping, Kroeze, Wesley K., Roth, Bryan L.
Vydáno v Mol Pharmacol (2016)

Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine(2A) Serotonin Receptor Functional Selectivity

Autor Strachan, Ryan T., Sciaky, Noah, Cronan, Mark R., Kroeze, Wesley K., Roth, Bryan L.
Vydáno 2010

Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method

Autor Abbas, Atheir I., Urban, Daniel J., Jensen, Niels H., Farrell, Martilias S., Kroeze, Wesley K., Mieczkowski, Piotr, Wang, Zefeng, Roth, Bryan L.
Vydáno 2010

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling

Autor Sheffler, Douglas J., Kroeze, Wesley K., Garcia, Bonnie G., Deutch, Ariel Y., Hufeisen, Sandra J., Leahy, Patrick, Brüning, Jens C., Roth, Bryan L.
Vydáno 2006

Single amino acid variation underlies species-specific sensitivity to amphibian skin-derived opioid-like peptides

Autor Vardy, Eyal, Sassano, Maria F., Rennekamp, Andrew J., Kroeze, Wesley K., Mosier, Philip D., Westkaemper, Richard B., Stevens, Craig W., Katritch, Vsevolod, Stevens, Raymond C., Peterson, Randel T., Roth, Bryan L.
Vydáno v Chem Biol (2015)

In silico design of novel probes for the atypical opioid receptor MRGPRX2

Autor Lansu, Katherine, Karpiak, Joel, Liu, Jing, Huang, Xi-Ping, McCorvy, John D., Kroeze, Wesley K., Che, Tao, Nagase, Hiroshi, Carroll, Frank I., Jin, Jian, Shoichet, Brian K., Roth, Bryan L.
Vydáno v Nat Chem Biol (2017)

Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders

Autor Zhu, Hu, Urban, Daniel J., Blashka, Jared, McPheeters, Matthew T., Kroeze, Wesley K., Mieczkowski, Piotr, Overholser, James C., Jurjus, George J., Dieter, Lesa, Mahajan, Gouri J., Rajkowska, Grazyna, Wang, Zefeng, Sullivan, Patrick F., Stockmeier, Craig A., Roth, Bryan L.
Vydáno 2012

Biased signaling of the proton-sensing receptor OGR1 by benzodiazepines

Autor Pera, Tonio, Deshpande, Deepak A., Ippolito, Michael, Wang, Bin, Gavrila, Adelina, Michael, James V., Nayak, Ajay P., Tompkins, Eric, Farrell, Eleni, Kroeze, Wesley K., Roth, Bryan L., Panettieri, Reynold A., Benovic, Jeffrey L., An, Steven S., Dulin, Nickolai O., Penn, Raymond B.
Vydáno v FASEB J (2018)

The Presynaptic Component of the Serotonergic System is Required for Clozapine's Efficacy

Autor Yadav, Prem N, Abbas, Atheir I, Farrell, Martilias S, Setola, Vincent, Sciaky, Noah, Huang, Xi-Ping, Kroeze, Wesley K, Crawford, LaTasha K, Piel, David A, Keiser, Michael J, Irwin, John J, Shoichet, Brian K, Deneris, Evan S, Gingrich, Jay, Beck, Sheryl G, Roth, Bryan L
Vydáno 2011

Allosteric ligands for the pharmacologically dark receptors GPR68 and GPR65

Autor Huang, Xi-Ping, Karpiak, Joel, Kroeze, Wesley K., Zhu, Hu, Chen, Xin, Moy, Sheryl S., Saddoris, Kara A., Nikolova, Viktoriya, Farrell, Martilias S., Wang, Sheng, Mangano, Thomas J., Deshpande, Deepak A., Jiang, Alice, Penn, Raymond B., Jin, Jian, Koller, Beverly H., Kenakin, Terry, Shoichet, Brian K., Roth, Bryan L.
Vydáno v Nature (2015)

Mast cell degranulation and fibroblast activation in the morphine-induced spinal mass: Role of Mas-related G protein-coupled receptor signaling.

Autor Yaksh, Tony L., Eddinger, Kelly A., Kokubu, Shinichi, Wang, Zhenping, DiNardo, Anna, Ramachandran, Roshni, Zhu, Yuelian, He, Yajun, Weren, Fieke, Quang, Daphne, Malkmus, Shelle A., Lansu, Katherine, Kroeze, Wesley K., Eliceiri, Brian, Steinauer, Joanne J., Schiller, Peter W., Gmeiner, Peter, Page, Linda M., Hildebrand, Keith R.
Vydáno v Anesthesiology (2019)