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Genetic Deletion of p90 Ribosomal S6 Kinase 2 Alters Patterns of 5-Hydroxytryptamine(2A) Serotonin Receptor Functional Selectivity

The concept of functional selectivity has now thoroughly supplanted the previously entrenched notion of intrinsic efficacy by explaining how agonists and antagonists exhibit a range of efficacies for distinct receptor-mediated responses. It is noteworthy that functional selectivity accommodates sign...

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Detalles Bibliográficos
Main Authors: Strachan, Ryan T., Sciaky, Noah, Cronan, Mark R., Kroeze, Wesley K., Roth, Bryan L.
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Pharmacology and Experimental Therapeutics 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835420/
https://ncbi.nlm.nih.gov/pubmed/19933401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.061440
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