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Antagonist Functional Selectivity: 5-HT(2A) Serotonin Receptor Antagonists Differentially Regulate 5-HT(2A) Receptor Protein Level In Vivo

Dysregulation of the 5-HT(2A) receptor is implicated in both the etiology and treatment of schizophrenia. Although the essential role of 5-HT(2A) receptors in atypical antipsychotic drug actions is widely accepted, the contribution of 5-HT(2A) down-regulation to their efficacy is not known. We hypot...

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Bibliografische gegevens
Hoofdauteurs: Yadav, Prem N., Kroeze, Wesley K., Farrell, Martilias S., Roth, Bryan L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The American Society for Pharmacology and Experimental Therapeutics 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186284/
https://ncbi.nlm.nih.gov/pubmed/21737536
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.111.183780
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