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Deorphanization of Novel Peptides and Their Receptors

Peptide hormones and neuropeptides play important roles in endocrine and neural signaling, often using G protein-coupled receptor (GPCR)-mediated signaling pathways. However, the rate of novel peptide discovery has slowed dramatically in recent years. Genomic sequencing efforts have yielded a large...

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Detalhes bibliográficos
Main Authors: Ozawa, Akihiko, Lindberg, Iris, Roth, Bryan, Kroeze, Wesley K.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895435/
https://ncbi.nlm.nih.gov/pubmed/20446073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12248-010-9198-9
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