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G Protein–Coupled Receptor Deorphanizations

G protein–coupled receptors (GPCRs) are major regulators of intercellular interactions. They initiate these actions by being activated by a wide variety of natural ligands. Historically, ligands were discovered first, but the advent of molecular biology reversed this trend. Most GPCRs are identified...

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Bibliografski detalji
Izdano u:Annu Rev Pharmacol Toxicol
Glavni autori: Civelli, Olivier, Reinscheid, Rainer K., Zhang, Yan, Wang, Zhiwei, Fredriksson, Robert, Schiöth, Helgi B.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5828024/
https://ncbi.nlm.nih.gov/pubmed/23020293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010611-134548
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