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G Protein–Coupled Receptor Deorphanizations
G protein–coupled receptors (GPCRs) are major regulators of intercellular interactions. They initiate these actions by being activated by a wide variety of natural ligands. Historically, ligands were discovered first, but the advent of molecular biology reversed this trend. Most GPCRs are identified...
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Publicado no: | Annu Rev Pharmacol Toxicol |
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Main Authors: | , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5828024/ https://ncbi.nlm.nih.gov/pubmed/23020293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010611-134548 |
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