Antimicrobial Peptides and Colitis

Por Ho, Samantha, Pothoulakis, Charalabos, Koon, Hon Wai
Publicado em 2013

Differentiating Functional Roles of Gene Expression from Immune and Non-immune Cells in Mouse Colitis by Bone Marrow Transplantation

Por Koon, Hon Wai, Ho, Samantha, Cheng, Michelle, Ichikawa, Ryan, Pothoulakis, Charalabos
Publicado em 2012

Substance P mediates antiapoptotic responses in human colonocytes by Akt activation

Por Koon, Hon-Wai, Zhao, Dezheng, Zhan, Yanai, Moyer, Mary P., Pothoulakis, Charalabos
Publicado em 2007

Insulin-like Growth Factor-1 Receptor Transactivation Modulates the Inflammatory and Proliferative Responses of Neurotensin in Human Colonic Epithelial Cells

Por Zhao, Dezheng, Bakirtzi, Kyriaki, Zhan, Yanai, Zeng, Huiyan, Koon, Hon Wai, Pothoulakis, Charalabos
Publicado em 2011

Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells

Por Zhao, Dezheng, Zhan, Yanai, Zeng, Huiyan, Koon, Hon Wai, Moyer, Mary P., Pothoulakis, Charalabos
Publicado em 2007

Substance P Stimulates Cyclooxygenase-2 and Prostaglandin E(2) Expression through JAK-STAT Activation in Human Colonic Epithelial Cells

Por Koon, Hon-Wai, Zhao, Dezheng, Zhan, Yanai, Rhee, Sang Hoon, Moyer, Mary P., Pothoulakis, Charalabos
Publicado em 2006

Cathelicidin Suppresses Colon Cancer Metastasis via a P2RX7-Dependent Mechanism

Por Wang, Jiani, Cheng, Michelle, Law, Ivy K.M., Ortiz, Christina, Sun, Mingjun, Koon, Hon Wai
Publicado no Mol Ther Oncolytics (2019)

Substance P-Mediated Expression of the Pro-Angiogenic Factor CCN1 Modulates the Course of Colitis

Por Koon, Hon-Wai, Zhao, Dezheng, Xu, Hua, Bowe, Collin, Moss, Alan, Moyer, Mary P., Pothoulakis, Charalabos
Publicado em 2008

High circulating elafin levels are associated with Crohn’s disease-associated intestinal strictures

Por Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Xie, Ying, Ho, Wendy, Mattai, S. Anjani, Shih, David Q., Koon, Hon Wai
Publicado no PLoS One (2020)

Neurotensin induces IL-6 secretion in mouse preadipocytes and adipose tissues during 2,4,6,-trinitrobenzensulphonic acid-induced colitis

Por Koon, Hon-Wai, Kim, You Sun, Xu, Hua, Kumar, Aatish, Zhao, Dezheng, Karagiannides, Iordanes, Dobner, Paul R., Pothoulakis, Charalabos
Publicado em 2009

Fidaxomicin Inhibits Clostridium difficile Toxin A-Mediated Enteritis in the Mouse Ileum

Por Koon, Hon Wai, Ho, Samantha, Hing, Tressia C., Cheng, Michelle, Chen, Xinhua, Ichikawa, Yoshi, Kelly, Ciarán P., Pothoulakis, Charalabos
Publicado em 2014

Therapeutic Mechanism of Macrophage Inflammatory Protein 1 α Neutralizing Antibody (CCL3) in Clostridium difficile Infection in Mice

Por Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Mukhopadhyay, Riya, Xie, Ying, Chen, Xinhua, Feng, Hanping, Pothoulakis, Charalabos, Koon, Hon Wai
Publicado no J Infect Dis (2020)

Substance P Induces CCN1 Expression via Histone Deacetylase Activity in Human Colonic Epithelial Cells

Por Koon, Hon Wai, Shih, David Q., Hing, Tressia C., Chen, Jeremy, Ho, Samantha, Zhao, Dezheng, Targan, Stephan R., Pothoulakis, Charalabos
Publicado em 2011

Substance P Modulates Colitis-Asscociated Fibrosis

Por Koon, Hon Wai, Shih, David, Karagiannides, Iordanes, Zhao, Dezheng, Fazelbhoy, Zafeer, Hing, Tressia, Xu, Hua, Lu, Bao, Gerard, Norma, Pothoulakis, Charalabos
Publicado em 2010

Sustained TL1A (TNFSF15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis

Por Zheng, Libo, Zhang, Xiaolan, Chen, Jeremy, Ichikawa, Ryan, Wallace, Kori, Pothoulakis, Charalabos, Koon, Hon Wai, Targan, Stephan R., Shih, David Q.
Publicado em 2013

Erratum: Sustained TL1A (TNFSF15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis (DOI: 10.1556/EuJMI.3.2013.1.2)

Por Zheng, Libo, Zhang, Xiaolan, Chen, Jeremy, Ichikawa, Ryan, Wallace, Kori, Pothoulakis, Charalabos, Koon, Hon Wai, Targan, Stephan R., Shih, David Q.
Publicado em 2013

Substance P Mediates Proinflammatory Cytokine Release From Mesenteric Adipocytes in Inflammatory Bowel Disease Patients

Por Sideri, Aristea, Bakirtzi, Kyriaki, Shih, David Q., Koon, Hon Wai, Fleshner, Phillip, Arsenescu, Razvan, Arsenescu, Violeta, Turner, Jerrold R., Karagiannides, Iordanes, Pothoulakis, Charalabos
Publicado no Cell Mol Gastroenterol Hepatol (2015)

Substance P promotes expansion of human mesenteric preadipocytes through proliferative and antiapoptotic pathways

Por Gross, Kara, Karagiannides, Iordanes, Thomou, Thomas, Koon, Hon Wai, Bowe, Collin, Kim, Ho, Giorgadze, Nino, Tchkonia, Tamara, Pirtskhalava, Tamara, Kirkland, James L., Pothoulakis, Charalabos
Publicado em 2009

Human Monoclonal Antibodies against Clostridium difficile Toxins A and B Inhibit Inflammatory and Histologic Responses to the Toxins in Human Colon and Peripheral Blood Monocytes

Por Koon, Hon Wai, Shih, David Q., Hing, Tressia C., Yoo, Jun Hwan, Ho, Samantha, Chen, Xinhua, Kelly, Ciarán P., Targan, Stephan R., Pothoulakis, Charalabos
Publicado em 2013

Fidaxomicin and OP-1118 Inhibit Clostridium difficile Toxin A- and B-Mediated Inflammatory Responses via Inhibition of NF-κB Activity

Por Koon, Hon Wai, Wang, Jiani, Mussatto, Caroline C., Ortiz, Christina, Lee, Elaine C., Tran, Diana Hoang-Ngoc, Chen, Xinhua, Kelly, Ciaran P., Pothoulakis, Charalabos
Publicado no Antimicrob Agents Chemother (2017)