Therapeutic Mechanism of Macrophage Inflammatory Protein 1 α Neutralizing Antibody (CCL3) in Clostridium difficile Infection in Mice

BACKGROUND: Clostridium difficile infection (CDI) causes diarrhea and colitis. We aimed to find a common pathogenic pathway in CDI among humans and mice by comparing toxin-mediated effects in human and mouse colonic tissues. METHOD: Using multiplex enzyme-linked immunosorbent assay, we determined th...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Wang, Jiani, Ortiz, Christina, Fontenot, Lindsey, Mukhopadhyay, Riya, Xie, Ying, Chen, Xinhua, Feng, Hanping, Pothoulakis, Charalabos, Koon, Hon Wai
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7184920/
https://ncbi.nlm.nih.gov/pubmed/31793629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiz640
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