Fidaxomicin Inhibits Clostridium difficile Toxin A-Mediated Enteritis in the Mouse Ileum

Clostridium difficile infection (CDI) is a common, debilitating infection with high morbidity and mortality. C. difficile causes diarrhea and intestinal inflammation by releasing two toxins, toxin A and toxin B. The macrolide antibiotic fidaxomicin was recently shown to be effective in treating CDI,...

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Detalhes bibliográficos
Main Authors: Koon, Hon Wai, Ho, Samantha, Hing, Tressia C., Cheng, Michelle, Chen, Xinhua, Ichikawa, Yoshi, Kelly, Ciarán P., Pothoulakis, Charalabos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135997/
https://ncbi.nlm.nih.gov/pubmed/24890583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02783-14
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