Increased substance P responses in dorsal root ganglia and intestinal macrophages during Clostridium difficile toxin A enteritis in rats

Previously we reported that pretreatment of rats with the substance P (SP) antagonist CP-96,345 inhibits the enterotoxic responses following administration of toxin A from Clostridium difficile into ileal loops, indicating that SP participates in the intestinal responses to this toxin. We now report...

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Bibliographic Details
Main Authors: Castagliuolo, Ignazio, Keates, Andrew C., Qiu, Bosheng, Kelly, Ciaran P., Nikulasson, Sigfus, Leeman, Susan E., Pothoulakis, Charalabos
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences of the USA 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC20803/
https://ncbi.nlm.nih.gov/pubmed/9114070
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