Sustained TL1A (TNFSF15) expression on both lymphoid and myeloid cells leads to mild spontaneous intestinal inflammation and fibrosis

TL1A is a member of the TNF superfamily, and its expression is increased in the mucosa of inflammatory bowel disease patients. Moreover, patients with certain TNFSF15 variants over-express TL1A and have a higher risk of developing strictures in the small intestine. Consistently, mice with sustained...

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Hlavní autoři: Zheng, Libo, Zhang, Xiaolan, Chen, Jeremy, Ichikawa, Ryan, Wallace, Kori, Pothoulakis, Charalabos, Koon, Hon Wai, Targan, Stephan R., Shih, David Q.
Médium: Artigo
Jazyk:Inglês
Vydáno: Akadémiai Kiadó 2013
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3638202/
https://ncbi.nlm.nih.gov/pubmed/23638306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1556/EuJMI.3.2013.1.2
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