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TL1A (TNFSF15) Regulates the Development of Chronic Colitis By Modulating both T helper (T(H)) 1 and T(H)17 Activation
BACKGROUND & AIMS: TL1A is a tumor necrosis factor-like molecule that mediates a strong costimulation of T helper (T(H)) 1 cells. Expression of TL1A is increased in the mucosa of Crohn’s disease patients and murine models of ileitis. The aim was to determine the possible role of TL1A in chronic...
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| Autores principales: | , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2008
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2605110/ https://ncbi.nlm.nih.gov/pubmed/18598698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.04.037 |
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